Has animal testing been reduced since the law was created/made?” and where has the decrease in animal testing been? for example like in makeup or medicine?

focusing on Animal Welfare Act and the separate amendments under the act. I also want to tap into the International,National, State and Local issues on animal testing. also, include my question “Has animal testing been reduced since the law was created/made?” and where has the decrease in animal testing been? for example like in makeup or medicine?